Must be taken 1–2 days before travel, daily while away, and then up to 4 weeks after returning Doxycycline 2.2 mg/kg body weight (maximum 100 mg) by mouth once daily for children aged ≥8 years.G6PD screening must be performed prior to primaquine use.Ĭhloroquine phosphate is the only formulation of chloroquine available in the United States 10 mg of chloroquine phosphate = 6 mg of chloroquine base.įor travel to chloroquine-resistant areas, preferred drugs are atovaquone/proguanil, doxycycline (for children aged ≥8 years) or mefloquine.įor Travel to Chloroquine-Resistant Areas: Equally recommended options include chloroquine, atovaquone/proguanil, doxycycline (for children aged ≥8 years), and mefloquine primaquine is recommended for areas with mainly P. Please refer to the following website for the most recent recommendations based on region and drug susceptibility: įor travel to chloroquine-sensitive areas. Recommendations are the same for HIV-infected and HIV-uninfected children. Starting 1 day before leaving, taken daily, and for 3–7 days after return Primaquine phosphate 0.6 mg/kg body weight base once daily by mouth, up to a maximum of 30 mg base/day.Mefloquine 5 mg/kg body weight orally given once weekly (max 250 mg).Must be taken 1-2 days before travel, daily while away, and then up to 4 weeks after returning
Atovaquone/proguanil once daily started 1–2 days before travel, for duration of stay, and then for 1 week after returning home.Start 1–2 weeks before leaving, take weekly while away, and then take once weekly for 4 weeks after returning home Chloroquine base 5 mg/kg body weight base by mouth, up to 300 mg once weekly (equivalent to 7.5 mg/kg body weight chloroquine phosphate).Dosage Recommendations for Prevention and Treatment of Malaria Indicationįor Travel To Chloroquine-Sensitive Areas:
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